Egypt’s population between 0-19 years of age in 2005 was projected to be 43% of the total population of 74 million. The US government SEER report, “Cancer Incidence and Survival in Children and Adolescents, 1975-1995”, stated that there is 150 children per million under 20 years diagnosed yearly with cancer. According to the WHO in their Global Action Against Cancer 2005 document, there are over 160,000 children globally diagnosed with cancer yearly, with 90,000 children dying yearly; 80% of these children live in developing countries. According to the SEER report, the probability of developing cancer before the age of 20 years is 1 in 300. Therefore, each year it is estimated that there are approximately 8400 children in Egypt estimated to develop cancer. Forty percent of these children will die due to lack of adequate treatment and facilities, as well as advanced technology. Today in the West, as a result of intensive treatments, state of the art facilities, and a specialized pediatric oncology healthcare team; 80-85%% of children survive cancer. Egypt, the Middle East and Africa need a centre of excellence dedicated only for children with cancer to achieve these rates. The Children’s Cancer Hospital Foundation (CCHF) was established in December 2003 and is headed by Egypt’s First Lady, Mrs. Suzanne Mubarak and a prestigious board of dignitaries including Dr. Fathy Sorour, as Vice President of the Board of Trustees who is not acting in his official capacity as Speaker of the Egyptian Parliament but as a private dedicated citizen. The Minister of Health, Governor of Cairo, and President of the Cairo University provide official government representation on the Board, while the rest of the membership is made up of members of the Egyptian Organization of Social and Cultural Development and AFNCI board members.